3-Chloromethyl-6,7-dimethyl-1,2-benzoxazole

5-Iodo-3-phenyl-2,1-benzoxazole

The title compound, C13H8INO, was prepared by a condensation reaction of 4-nitro-benzene with phenyl-acetonitrile in NaOH-ethanol solution. There are two independent mol-ecules in the asymmetric unit, in which the dihedral angles between the benzene ring and the benzoisoxazole unit are 4.2 (3) and 4.1 (3)°. The crystal packing is governed by C-H⋯N, C-I⋯π and C-I⋯O inter-actions.

3-Benzyl-5-methyl-1,2-benzoxazole 2-oxide

In the title compound, C(15)H(13)NO(2), the isoxazole unit and the attached benzene ring are almost coplanar, making a dihedral angle of 1.42 (8)°. The benzyl ring is inclined to the isoxazole ring by 74.19 (8)° and is in a +sc conformation with respect to the benzisoxazole unit. In the crystal, C-H⋯O hydrogen bonds link the mol-ecules, forming zigzag chains propagating along the b axis. There ...

Bioassay of 3-(chloromethyl) pyridine hydrochloride for possible carcinogenicity.

A bioassay of 3-(chloromethyl)pyridine hydrochloride for possible carcinogenicity was conducted by administering the test chemical by gavage to Fischer 344 rats and B6C3F1 mice. Groups of 50 rats and 50 mice of each sex were administered 3-(chloromethyl)pyridine hydrochloride in a vehicle of distilled water three times per week at one of the following doses, either 75 or 150 mg/kg body weight f...

3-[Chloro­(phen­yl)meth­yl]-6-methyl-1,2-benzoxazole

The title compound, C(15)H(12)ClNO, is a functionalized 1,2-benzoxazole with a chloro-(phen-yl)methyl substituent. The mol-ecule is V-shaped, the dihedral angle between the mean plane of the 1,2-benzoxazole system [maximum deviation = 0.023 (3) Å for the N atom] and the phenyl ring being 70.33 (14)°. There are no hydrogen-bonding inter-actions in the crystal structure, which is stabilized by va...

Dimethyl Carbonate PERP 2012 S 12 Report